Peripheral immune tolerance restrains mature lymphocytes outside primary lymphoid organs, preventing harmful responses to self and harmless environmental antigens.
peripheral-immune-tolerancePharmacologyPharmacology is the science of drug actions, their movement through living organisms, and their beneficial and harmful effects.
pharmacologyPhysiologyPhysiology is the study of how living organisms function, from molecular and cellular mechanisms to coordinated whole-organism processes.
physiologyPrevalencePrevalence is the proportion of a defined population that has a disease, condition, or characteristic at a specified time or during a specified period.
prevalencePrimary Health CarePrimary health care is a whole-of-society approach combining integrated health services, action on health determinants, and community participation.
primary-health-carePublic HealthPublic health is the organized effort to prevent disease, protect health, and improve well-being across populations through research, services, policy, and collective action.
public-healthPublic Health SurveillancePublic health surveillance is the systematic collection, analysis, interpretation, and communication of health data to inform population-level prevention and response.
public-health-surveillanceQuality of LifeQuality of life is a multidimensional concept encompassing people’s living conditions, functioning, relationships, and subjective evaluations of their lives.
quality-of-lifeRegulatory T CellA regulatory T cell is a specialized T lymphocyte that restrains immune responses, maintains self-tolerance, and helps control inflammation.
regulatory-t-cellRehabilitationRehabilitation comprises person-centred interventions that improve or maintain functioning, reduce disability, and support participation in everyday life.
rehabilitationRheumatoid ArthritisRheumatoid arthritis is a chronic autoimmune disease that causes joint inflammation and can damage joints and affect other organs.
rheumatoid-arthritisSickle Cell DiseaseSickle cell disease is a group of inherited hemoglobin disorders that cause red blood cell sickling, anemia, painful episodes, and potentially serious organ damage.
sickle-cell-diseaseSmallpoxSmallpox was a contagious disease caused by variola virus, eradicated worldwide through vaccination and coordinated surveillance, with eradication formally declared in 1980.
smallpoxSocial Determinants of HealthSocial determinants of health are the social, economic, and environmental conditions that shape health outcomes and their distribution across populations.
social-determinants-of-healthStrokeStroke is sudden brain injury caused by interrupted blood flow or bleeding, potentially resulting in neurological disability or death.
strokeSurgerySurgery is the medical discipline concerned with operative treatment, diagnosis, and the care of patients before and after procedures.
surgerySynapseA synapse is a specialized junction through which a neuron communicates with another neuron or a target cell by chemical or electrical signaling.
synapseSystemic Lupus ErythematosusA chronic autoimmune disease with variable inflammatory effects on the skin, joints, blood, kidneys, and other organs.
systemic-lupus-erythematosusT-Cell CostimulationT-cell costimulation comprises receptor-mediated signals that complement antigen recognition and regulate T-cell activation, proliferation, survival, and differentiation.
t-cell-costimulationThymusThe thymus is a primary lymphoid organ where T cells mature and undergo selection that supports immune defense and tolerance to the body’s own tissues.
thymusTraditional Chinese MedicineTraditional Chinese medicine is a medical system that developed in China, encompassing distinctive diagnostic and therapeutic theories and practices such as Chinese materia medica, acupuncture, and moxibustion.
traditional-chinese-medicineType 1 DiabetesType 1 diabetes is a chronic disease, usually autoimmune, in which destruction of pancreatic beta cells causes severe insulin deficiency and elevated blood glucose.
type-one-diabetesUniversal Health CoverageUniversal health coverage means access to needed, quality health services for everyone without financial hardship.
universal-health-coverageVaccineA vaccine is a biological preparation that stimulates specific immune responses to prevent disease or, in some applications, treat an existing condition.
vaccineWorld Health OrganizationThe World Health Organization is the United Nations specialized agency responsible for international health cooperation, technical standards, and coordination of responses to health emergencies.
world-health-organization